Today, everyone along the pharma value chain—patients, physicians, pharmacists, payers, commissioners, regulators, and government authorities—have a digital “self” that is generally far more open to sharing in cyberspace than in the real world. Machine learning, mHealth, cloud, advanced analytics, IoT, Artificial Intelligence, AR, VR, Predictive Analytics, RPA, Blockchain are among key the innovations that are transforming the healthcare industry. The industry has been dipping a toe in the digital waters, but now it’s time to take the plunge. However, even with all the advances, many experts on these issues find it difficult to determine what initiatives to expand and how, since they are still unclear how digital success will be in terms of health.